* indicates playoff game
TmOppDatePFPADeficitSan Francisco 49ersNew Orleans SaintsDec 7, 1980383528San Francisco 49ersNew York GiantsJan 5, 2003*393824San Francisco 49ersIndianapolis ColtsOct 18, 1998343121San Francisco 49ersCincinnati BengalsOct 20, 1996282121San Francisco 49ers@Chicago BearsOct 18, 1953352821San Francisco 49ers@Philadelphia EaglesOct 2, 2011242320San Francisco 49ersLos Angeles RamsOct 4, 1953313020San Francisco 49ers@Detroit LionsOct 16, 1955272418San Francisco 49ers@Los Angeles RamsJan 9, 2022272417San Francisco 49ers@Atlanta FalconsJan 20, 2013*282417San Francisco 49ers@Los Angeles RamsDec 11, 1989302717San Francisco 49ers@Buffalo BillsSep 28, 1947412417San Francisco 49ersArizona CardinalsNov 17, 2019362616San Francisco 49ersArizona CardinalsOct 10, 2004312816San Francisco 49ersCarolina PanthersNov 8, 1998252316San Francisco 49ers@Los Angeles RamsDec 24, 2016222114San Francisco 49ers@St. Louis RamsOct 13, 2014311714San Francisco 49ers@Seattle SeahawksSep 14, 2008333014San Francisco 49ers@Atlanta FalconsOct 14, 2001373114San Francisco 49ers@Detroit LionsOct 9, 1994272114TmOppDatePFPADeficitSan Francisco 49ers@Houston OilersOct 7, 1990242114San Francisco 49ers@New Orleans SaintsOct 8, 1989242014San Francisco 49ersSt. Louis CardinalsOct 18, 1987342814San Francisco 49ers@Green Bay PackersOct 26, 1986311714San Francisco 49ersNew Orleans SaintsNov 27, 1977201714San Francisco 49ers@Los Angeles RamsNov 9, 1975242314San Francisco 49ersLos Angeles RamsNov 21, 1965302714San Francisco 49ersDallas CowboysNov 10, 1963312414San Francisco 49ersChicago BearsOct 27, 1957211714San Francisco 49ers@New Orleans SaintsDec 8, 2019484613San Francisco 49ers@St. Louis RamsDec 21, 2008171613San Francisco 49ers@Denver BroncosDec 31, 2006262313San Francisco 49ers@St. Louis RamsDec 24, 2005242013San Francisco 49ersNew Orleans SaintsNov 15, 1992212013San Francisco 49ers@Cincinnati BengalsSep 20, 1987272613San Francisco 49ersDallas CowboysDec 22, 1985311613San Francisco 49ers@Denver BroncosSep 23, 1973363413San Francisco 49ersAtlanta FalconsDec 6, 1970242013San Francisco 49ersPhiladelphia EaglesDec 21, 1969141313San Francisco 49ersGreen Bay PackersDec 1, 1968272013TmOppDatePFPADeficitSan Francisco 49ersPittsburgh SteelersSep 28, 1958232013San Francisco 49ersLos Angeles RamsDec 21, 2019343111San Francisco 49ersPhiladelphia EaglesSep 28, 2014262111San Francisco 49ers@Philadelphia EaglesSep 24, 1989382811San Francisco 49ers@Los Angeles RamsOct 23, 1983453511San Francisco 49ersMinnesota VikingsDec 16, 1972201711San Francisco 49ers@New Orleans SaintsDec 13, 1970382711San Francisco 49ersDetroit LionsDec 5, 1965171411San Francisco 49ers@Washington RedskinsNov 16, 1952231711San Francisco 49ers@Las Vegas RaidersJan 1, 2023373410
